Among the top 10 DRGs identified from TCGA-STAD dataset, six are GC related (E2F1 [50], AK1B10 [51], CEBPA [52], PTK7 [53], RASAL1 [54], GKN [55]), and three are cancer related (DPCR1 [56], GGT6 [57], RAB25 [58]). This evidence concerns the gene E2F1 and cancer.