For example, ZEB1 facilitates bone‐specific metastasis of breast carcinomas by inducing expression of noggin, follistatin and chordin‐like 1, extracellular antagonists that inactivate ligands of the activin, and bone morphogenetic protein branches of the TGFβ family (Mock et al., 2015). This evidence concerns the gene TGFB1 and breast carcinoma.