HP and melanoma: Considering a selection criteria of p value < 0.01 or abs (log2 (FC)) > 1 as a cutoff, 18 proteins were selected as significantly more abundant in the melanoma-derived lysate TRIMEL (with HS conditioning) when compared with the nontreated (no-HS) samples (Figure 3(b) and Table 1), being haptoglobin (HP) one of the most overexpressed protein, since it fulfilled both selection criteria.