To determine whether PCBP2 promoted the viability of human gastric cancer cells as mediated by CDK2, HGC‐27 cells were co‐transfected with shPCBP2#1 (designated as shPCBP2) or shControl and CDK2 plasmid or control, and cell viability assays were performed. The gene discussed is PCBP2; the disease is gastric cancer.