IL1B and periodontitis: In periodontitis patients, il‐1β was found to be higher in deep active lesions compared to healthy gingiva (Fujita, Ito, Sekino, & Numabe, 2012; Gamonal, Acevedo, Bascones, Jorge, & Silva, 2000; Oh, Hirano, Takai, & Ogata, 2015; Reis, Da Costa, Guimaraes, et al., 2014; Thunell, Tymkiw, Johnson, et al., 2010; Toker, Poyraz, & Eren, 2008).