HBEGF and neoplasm: Tang et al. [7] used MC38 tumor and A20 (B lymphoma) tumor cells, and PD-L1 knockout mice, BM transplantation chimera mice, CD11b-DTR (diphtheria toxin receptor) mice, as well as various depletion antibodies, to address the contribution of PD-L1 from relevant cells in checkpoint blockade therapy.