SOD1 and type 2 diabetes mellitus: In animals with experimental T2DM, CUR impaired hyperglycemia-induced oxidative stress through the normalization of the activity of hepatic antioxidant enzymes such as SOD, CAT, and GPx and a reduction of lipid peroxidation, as reflected by the decreased level of the end product of lipid peroxidation—malondialdehyde (MDA) [17].