CD4 and cutaneous leishmaniasis: The ratio between regulatory FoxP3+ and effector CD4+ T cells, as well as the ratio between positive cytokines (TGF-β+ and IL-10+) and FoxP3+ and CD4+ T cells in NUCL and normal skin, was assessed in order to better evaluate the participation of regulatory cells in the cutaneous inflammation caused by atypical cutaneous leishmaniasis.