The effects of ced-3 RNAi and of the drp-1(tm1108) mutation on muscle cells of dys-1(cx18);hlh-1(cc561ts) were cumulative indicating that CED-3 probably has an additional role in dystrophin-dependent muscle degeneration, which is DRP-1-independent. This evidence concerns the gene IFT43 and Skeletal muscle atrophy.