Indeed, a significantly higher mean APC11 mRNA expression was observed in aneuploid compared to diploid and near diploid colon cancer cell lines (CIN: mean mRNA = 1.904; 95% CI = 1.386–2.616; vs. Diploid: mean mRNA = 0.999; 95% CI = 0.774–1.291; P for comparison <0.001), and MSI cell lines exhibited a lower mean level of APC11 (MSI: mean mRNA = 1.11; 95% CI = 0.817–1.508; vs. MSS: mean mRNA = 1.962; 95% CI = 1.635–2.355; P for comparison <0.001). This evidence concerns the gene ANAPC11 and malignant colon neoplasm.