Consistent with these results, silencing of GADD45α in the GADD45α-high expressing cervical cancer cell lines CasKi and SiHa (Supplementary Fig. 1) also protected these two cell lines from IR-induced cell death, DNA damage, apoptosis, and cell cycle arrest (Supplementary Figs. 1 and 2). Here, GADD45A is linked to cervical cancer.