Thus, we demonstrate an inverse correlation between Kindlin-2 and miR-200b in the aggressive and mesenchymal BC cells vs their non-aggressive and epithelial counterparts, which strongly suggest the involvement of Kindlin-2 in the miR-200b-mediated regulation of the EMT and that miR-200b is involved in the regulation of Kindlin-2 during this process. Here, FERMT2 is linked to breast cancer.