Support for the idea of a role for DCs in measles pathogenesis was provided by an earlier in vitro study by de Witte and coworkers in which the authors demonstrated that CD150 and C-type lectin DC-SIGN, which facilities virus transfer to T-lymphocytes, are both involved in DC infection and subsequent spread of de novo synthesized virus (19). The gene discussed is SLAMF1; the disease is measles.