Surprisingly, RNAi depletion of each of these subunits resulted in neither proprioceptive defects (when depleted in sensory neuron precursors) nor male infertility nor sperm immotility (when depleted in spermatocytes; Uri, 4 independent RNAi lines; Uxt, 3 lines; Pdrg1/CG15863, 1 line; for sperm motility, n = 10 males for each line). This evidence concerns the gene PDRG1 and male infertility.