The findings showed that the common variants rs671 at ALDH2 gene were associated with an increased risk of CAD in South Chinese, while not in North Chinese.[6] In the present study, our primary objective was to explore whether the single nucleotide polymorphisms (SNPs) at ALDH2 gene were associated with the cardiovascular outcome and its individual endpoints, and discussed its possible mechanism. Here, ALDH2 is linked to coronary artery disorder.