Importantly, urolithin A alsoregulated the Lin28a/let-7a axis in transient HBx-transfected HCC HepG2 cells.Furthermore, urolithin A decelerated the HepG2.2.15 cell invasion, which wasinvolved in suppressing the let-7a downstream factors HMGA2 and K-ras. Here, KRAS is linked to hepatocellular carcinoma.