In the pemphigus foliaceus (PF) subgroup, only antibodies against Dsg1 are present, whereas in pemphigus vulgaris (PV) antibodies against Dsg3 are found in mucosal dominant PV (mdPV), or together with anti-Dsg1 in mucocutaneous PV (mcPV) (2). This evidence concerns the gene DSG3 and pemphigus foliaceus.