ANGPT2 and bacterial infectious disease with sepsis: Ang2 levels were also associated with other clinical correlates of disease severity including Acute Physiology and Chronic Health Evaluation II (APACHE II) scores (56, 155, 161, 167), ICU length of stay (60), bacteremia (159), positive fluid balance (151, 162), need for corticosteroid support (151), and measures of organ failure (50, 53, 56, 60, 151–155, 160, 161, 164, 167, 169).