SFV- and VEE-based vaccines against HPV16 E6/E7 have demonstrated the ability to induce specific CTLs that can kill HPV16 E6/E7-expressing tumour cells in vitro and clear tumours in mouse models (124–126), including in the HLA-A*0201 transgenic mice (127, 128). This evidence concerns the gene HLA-A and neoplasm.