Statistical results demonstrated that the patients’ age, gender, smoking (yes/no), family history (yes/no), tumor site (colon/rectum), primary tumor size (≤4/>4 cm), differentiated degree (high/middle/poor), carbohydrate antigen 199 (high/normal), carcinoembryonic antigen (high/normal), lymph node metastases, systemic chemotherapy (yes/no), radiotherapy (yes/no) and R0 after metastasis (yes/no) didn’t differ obviously between the two groups. The gene discussed is CEACAM5; the disease is neoplasm.