Kaplan-Meier analysis indicated that smoking history (P = 0.028), primary tumor size (P = 0.023), invasion of the serous membrane (P < 0.001), primary tumor differentiation (P < 0.001), pathological classification (P = 0.005), lymph node metastasis (P < 0.001), and carcinoembryonic antigen (CEA) >5 ng/mL (P = 0.010) were obviously correlated with decreased median survival time. The gene discussed is CEACAM5; the disease is metastatic malignant neoplasm in the lymph nodes.