Interestingly in two independent datasets – the Chinese Cancer Genomics Consortium (CCGC) and REpository for Molecular BRAin Neoplasia DaTa (REMBRANDT) – EEA1 expression increases from normal brain to GBM, and survival is significantly better for patients with tumors having lower expression of EEA1 (Fig. 5d–f). This evidence concerns the gene EEA1 and neoplasm.