In fact, an exploratory, hypothesis-generating analysis of TERT gene promoter mutations and CDKN2A homozygous deletions in the adenomyoepitheliomas subjected to massively parallel sequencing revealed a significant association with the presence of a carcinoma (Fig. 2, TERT gene promoter mutations, P = 0.0307, and CDKN2A homozygous deletions, P = 0.0086, Fisher’s exact tests). This evidence concerns the gene TERT and carcinoma.