AR was expressed in ≥10% of tumor cells (the cut-off employed to select patients for potential anti-androgen therapy11) in all but one (26/27, 96%) ER-positive adenomyoepitheliomas, but in 9/16 (56%) ER-negative adenomyoepitheliomas (P < 0.01, Fisher’s exact test, Fig. 1i, Supplementary Figs. 1c, i). This evidence concerns the gene AR and neoplasm.