In experimental mouse models of melanoma metastasis, the inhibition of de novo FA synthesis with Orlistat or thiazolidinediones, or by inhibiting mitochondrial FA β-oxidation with drugs such as etomoxir, a carnitine palmitoyltransferase 1A (CPT1) inhibitor, had anti-tumour effects (Malvi et al., 2015; Nieman et al., 2011; Seguin et al., 2012). This evidence concerns the gene CPT1A and melanoma.