ANGPTL4 and osteosarcoma: Although there was no correlation between ANGPTL4 expression levels in non-metastatic osteosarcoma versus osteosarcoma that had metastasised, we did find an increase in ANGPTL4 expression in stage 2 disease (osteosarcoma that has spread beyond the bone) versus either stage 1 (osteosarcoma that has not grown outside the bone) or stage 3 (osteosarcoma that has metastasised to another body site).