A recent study reported that two small molecule inhibitors PF-573228 and PF-431396, dual specificity inhibitors of FAK and PYK2, as well as another small molecule inhibitor VS-6063 (specifically inhibits FAK but not PYK2), could inhibit cancer cell growth and anchorage-independent colony formation and induce apoptosis and cell cycle arrest [91]. The gene discussed is PTK2B; the disease is cancer.