Results of this study revealed that CAPE-treated NPC cells had significantly increased phosphorylation of ERK, JNK, and p38 in a dose- and time-dependent manner (Figure 5A–C), which was consistent with previous studies showing the similar observations in C6 glioma and oral squamous carcinoma cells [14,37]. This evidence concerns the gene MAPK8 and nasopharyngeal carcinoma.