Our result clearly showed that NDRG1, but not NDRG2 and NDRG3, was induced by CAPE in EBV-negative NPC TW04 cells in a dose-dependent manner, which was proved by western blot, RT-qPCR, and reporter assay (Figure 2) and consistent with our previous finding in oral cancer which showed only NDRG1 would be induced after CAPE treatment [14]. This evidence concerns the gene NDRG1 and lip and oral cavity carcinoma.