MTOR and chronic kidney disease: An animal model of CKD-related LVH found anactivation of cellular mTOR pathway, even in the absence of pressure or volumeexpansion.16 Other experimental modelsand post-renal transplantation patients have shown that cell mTOR pathway wasinhibited by the use of rapamycin (mTOR inhibitor partial), which led to asignificant reduction in LV mass.