IGHE and asthma: [50] evaluated the efficacy of SLIT in patients with allergic asthma in order to provide reliable evidence for clinical application of SLIT. It showed that, compared with control group, SLIT could significantly reduce asthma symptom scores (SMD [95%CI], −0.89 [−1.36, −0.43]) and asthma medication scores (SMD [95%CI], −4.53 [−6.97, −2.08]), but neither first second forced expiratory volume (FEV1) (SMD [95%CI], 0.19 [−0.02, 0.41]; p = 0.078), nor serum IgE levels (SMD [95%CI], 0.05 [−0.58, 0.69]; p = 0.870).