One study subject experienced clinically significant laboratory elevations in serum alanine aminotransferase (peak 5.5 × ULN; grade 3) and aspartate aminotransferase (peak 3.8 × ULN; grade 2) from day 26 to day 36, which were considered to be attributable to the onset of a new cytomegalovirus infection (diagnosed by changes in immunoglobulin M and immunoglobulin G values) and not to any of the three study drugs. The gene discussed is GPT; the disease is cytomegalovirus infection.