Thus, it was proposed that targeting pancreatic cancer cell metabolism might be helpful for discovering novel therapeutic targets and pancreatic cancer cells might be starved by “cutting the fuel supply.” In our present study, we demonstrated that MPD could inhibit the glycolysis and suppressed the expression of key glycolysis genes, including Glut1, HK2, and LDHA. This evidence concerns the gene LDHA and familial pancreatic carcinoma.