IGF2BP2 and metabolic dysfunction-associated steatotic liver disease: More convincingly, mice with liver-specific overexpression of IGF2BP2 show more fat deposition and an earlier and more intense fibrogenesis than their wild-type littermates when they are fed a methionine-choline-deficient (MCD) diet [101], suggesting a driving role of IGF2BP2 in the pathogenesis of NAFLD [101].