In NSCLC, YAP overexpression has been associated with development, progression, and poor prognosis [72,73,74,75,76,77] similar to TAZ [78,79,80], and an epidemiological study showed that a germline YAP mutation resulting in its oncogenic hyperactivation is associated with the occurrence of lung cancer [81]. This evidence concerns the gene YAP1 and non-small cell lung carcinoma.