YAP1 and non-small cell lung carcinoma: Interestingly, in adults, YAP and TAZ are not required for normal tissue homeostasis, while numerous experimental results show that nuclear YAP and TAZ are required to drive lung tumor formation, survival, stemness, progression, metastasization, and resistance to therapy, in particular in non-small cell lung cancer (NSCLC) that will be thoroughly described in the following sections.