TP53 and dyskeratosis congenita: The p53Δ31/Δ31 mice develop severe phenotypes of telomere syndromes and especially of DC (see Table 1 for a detailed comparison between DC features and p53Δ31/Δ31 mice phenotypes) in the first generation of intercrosses, which suggests that the impact of p53 activation on telomere biology is multifactorial.