Another recent study showed that the probiotic (containing Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum and Lactobacillus fermentum) administration for three months has favorable effects on Mini–Mental State Examination (MMSE) score, malonyl dialdehyde (MDA), high sensitive C-reactive protein (hs-CRP), markers of insulin metabolism and triglycerides levels of the AD patients [62]. This evidence concerns the gene CRP and Alzheimer disease.