To further explored whether FABP4 could suppress the growth of HCC cells in vivo, control, and FABP4‐overexpressing YY‐8103 cells were injected into the subcutaneously of nude mice to monitored the tumor growth (Fig. 4A).The average tumor volume in the FABP4‐overexpressing group was significantly suppressed compared with those in the control group (n = 4, P < 0.01; Fig. 3B). Here, FABP4 is linked to hepatocellular carcinoma.