Finally, in a model of acute myocardial infarction, VEGFB−/− mice demonstrated reduced revascularization of the ischemic border 7 days post MI as a consequence of fewer thrombomodulin positive capillaries and smooth muscle α-actin positive covered vessels in the infarct area compared to wildtype animals (42). The gene discussed is THBD; the disease is myocardial infarction.