LRRK2 and Parkinson disease: As previously reported (Wang B. et al., 2015), PD-like neurodegenerative phenotypes were demonstrated in Elav-α-synuclein-WT, Elav-α-synuclein-A53T, Elav-Q311X (Parkin mutation) and Ddc-GS2 (LRRK2 mutation) transgenic fruit fly (Drosophila melanogaster).