MAPT and Alzheimer disease: To investigate the contribution of TAOKs to the development of tau pathology and disease progression in AD, serial sections were prepared from the entorhinal cortex of AD brain displaying mild (Braak stage II, n = 3), moderate (Braak stage IV, n = 3) or severe (Braak stage VI, n = 4) pathology alongside control brain (n = 4) (Additional file 1: Table S1) [5].