Nuclear Snail1 also becomes poly‐ADP‐ribosylated by interacting with the chromatin‐bound enzyme poly‐ADP‐ribose polymerase 1 (PARP‐1), which also prolongs the stability and nuclear residence of Snail1, thus contributing to breast cancer EMT and invasiveness (Rodriguez et al., 2011). This evidence concerns the gene SNAI1 and breast carcinoma.