CISH and hepatocellular carcinoma: Our results may provide an explanation for the high de novo recurrence of HBV‐related HCC after PH, probably through induction of the sequential changes of LR‐related SOCS family proteins, growth factors, and transcription factors, which promote growth on the precancerous remnant liver (Fig. 5; Chok et al., 2011; Iizuka et al., 2003; Sonnenblick and Zahavi, 2017).