H2AZ1 and hepatocellular carcinoma: H2A histone family member Z, H2AFZ (1.7 fold overexpressed; p-value ≤ 0.05) which showed inverse relationship with miR-200a-3p and miR-141-3p has been reported to be highly expressed in breast, prostate, bladder and hepatocellular cancers and enhances tumorigenesis by accelerating cell cycle and epithelial to mesenchymal transition55–57.