From the initial number of type 1 diabetic patients recruited (n = 397) in the study, five patients were excluded for presenting an eGFR < 60 mL/min, two patients were excluded for presenting a urine albumin/creatinine ratio > 300 mg/g, three patients were excluded for presenting cardiovascular disease and 11 patients were excluded for presenting with one or more ophthalmic exclusion criteria. The gene discussed is ALB; the disease is cardiovascular disorder.