PTX3 and chronic kidney disease: The levels of plasma PTX3 in early acute ischemia-reperfusion renal injuries and chronic kidney disease are response to be increased [23, 24], and the expression of PTX3 in the renal tubular epithelial cells during ischemia-reperfusion kidney injuries and the glomerular endothelial cells in patients with IgA nephropathy [13] and type I membranous proliferative glomerulonephritis were increased.