The co-culture of tumor cells with IL-2 stimulated allogeneic breast cancer, PDAC, or OC patients’ PBL, respectively, in the absence of trastuzumab induced a delayed lysis of MCF-7 cells, a low lysis rate of PancTu-I cells and an obvious lysis of OC1 cells (Figure 1A) in comparison to the trastuzumab-mediated lysis suggesting an IL-2-mediated activation of PBL effector cells. Here, IL2 is linked to breast cancer.