KCNQ1 and long QT syndrome 1: Loss-of-function mutations in several genes have been linked to LQTS (LQT1-LQT13), with around 70% occurring in genes encoding pore-forming subunits for the primary repolarizing K+ currents in ventricular cardiomyocytes – KCNQ1 (LQT1) and hERG (LQT2) (Bohnen et al., 2016).