We report three lncRNAs that differentiate aggressive and indolent prostate cancers: the well-known SChLAP1 transcript, AC009014.3, and a newly discovered transcript named XPLAID that is transcribed from a gene desert on the X-chromosome, a location that evokes the linkage [29] between X-chromosome variations and hereditary prostate cancer. The gene discussed is SCHLAP1; the disease is prostate cancer, hereditary.