PAPPA and breast carcinoma: The baseline patient, tumor, and treatment characteristics according to tertiles of IGFBP‐2 and PAPP‐A are shown in Table 1 for the 301 women (with complete NPI and IGF data) with early‐breast cancer treated by surgery (with and without adjuvant therapies) at the Odense University Hospital, from 1993 to 1998.