Insulin‐like growth factor ligands have well‐established tumor developing properties at a cellular level 7 and in the circulation, the concentration of IGF‐I, and to a lesser extent that of IGFBP‐3, are associated with subsequent risk of developing prostate, pre‐ and postmenopausal breast cancer and colorectal cancer 8. Here, IGFBP3 is linked to breast carcinoma.