ESR1 and neoplasm: For PD‐IDC and IDC, the significant characteristics were race (P = 0.011), marital status (P < 0.001), tumor size (P < 0.001), lymph node status (P < 0.001), Grade (P < 0.001), AJCC stage (P < 0.001), ER status (P < 0.001), PR status (P < 0.001), HER2 status (P < 0.001), and whether had radiation treatment (P < 0.001).