Meanwhile, the significant indicators of PD‐DCIS were age at diagnosis (P < 0.001), marital status (P < 0.001), tumor size (P < 0.001), lymph node status (P < 0.001), AJCC stage (P < 0.001), HER2 status (P < 0.001), and radiation or not (P = 0.007). This evidence concerns the gene ERBB2 and ductal breast carcinoma in situ.