ESR1 and neoplasm: Using the Pearson's chi‐square test, for PD and IDC, the significant variables were age (P < 0.001), marital status (P < 0.001), laterality (P < 0.001), tumor size (P < 0.001), lymph node status (P < 0.001), Grade (P < 0.001), AJCC stage (P < 0.001), ER (estrogen receptor) status (P < 0.001), PR (progesterone receptor) status (P < 0.001), HER2 (human epidermal growth factor receptor 2) status (P < 0.001), and whether had radiation treatment (P < 0.001).