For PD‐DCIS and IDC, the considerable characteristics were age (P < 0.001), marital status (P < 0.001), tumor size (P < 0.001), Grade (P < 0.001), AJCC stage (P < 0.001), ER status (P < 0.001), PR status (P < 0.001), HER2 status (P < 0.001), and whether had radiation treatment (P < 0.001). The gene discussed is ESR1; the disease is neoplasm.