MAPK8 and obesity due to melanocortin 4 receptor deficiency: We were able to evidence the ability of anthocyanins to decrease in vivo the phosphorylation of JNK/SAPK p46 stress kinase, thus providing a new insight into the mechanism of phenolic compounds in the treatment of inflammation in adipose tissues, a field of currently study since the lack of a better knowledge of the mechanisms that regulate or control ATM in pathologies such as obesity and metabolic disorders.