With the aim to improve the tumor diagnosis and treatment further, Du et al. from our lab recently fabricated a PD-L1 targeted multifunctional cerasomal NPs loaded with chemotherapeutic drug PTX and labeled with IRDye800CW and Gd-DOTA to facilitate dual mode NIRF and MR image-guided chemotherapy (Du et al., 2018). This evidence concerns the gene CD274 and neoplasm.